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Formal Name: [3-[2-[ethyl(methyl)amino]ethyl]-1H-indol-4-yl] acetate

Synonyms: 4-Acetoxy-N-methyl-N-ethyltryptamine
Molecular Formula: C15 H20 N2 O2 . C4 H4 O4

Cas Number: 1445751-40-5

SKU: 4-Acetoxy-N-ethyl-N-methyltryptamine Category:


What is 4-AcO-MET

4-AcO-MET is short for 4-Acetoxy-N-ethyl-N-methyltryptamine. This chemical belongs to the tryptamine category. Although 4-AcOMET is a less well-known tryptamine it still produces psychedelic effects, just like other tryptamines. Similar to other 4-AcO chemicals such as 4-AcO DMT or 4-AcO–DET, 4-AcO is also known as 4-AcO MET. It also shares a chemical structure with psilocybin (the active ingredient in magic mushrooms).

4-AcO-MET is a synthetic psychedelic compound that is sometimes used in research for its effects on serotonin receptors in the brain. It is a structural analog of psilocin and produces similar effects such as altered perception, mood, and thought patterns.

As with all research chemicals, it is important to handle 4-AcO-MET with care and caution. Researchers should be well-informed about the proper safety precautions, dosing guidelines, and potential risks associated with its use. It is also important to ensure that research is conducted in accordance with local regulations and ethical guidelines.

It is not recommended to use 4-AcO-MET for any purposes other than research, as its effects on the brain and body are not fully understood and could be potentially dangerous. If you have any questions or concerns about the use of 4-AcO-MET in research, it is best to consult with a qualified professional or a reputable research institution.


4-AcO-MET or 4-Acetoxy-N-methyl-N-ethyltryptamine is a synthetic indole alkaloid molecule of the tryptamine class. The core structure of tryptamines is composed of a bicyclic, indole heterocycle that is attached at R3 and an amino group via an electron side chain. 4-AcO–MET is replaced at R4 by an acetoxy functional group CH3COO+ in its indole heterocycle. It also has a methyl and an ethyl chains bound to the terminal amino RN of its tryptamine-backbone (MET). 4-AcO–MET is an analog to 4-HO-MET, and the N-substituted homolog of 4-AcO–DMT.

4-AcO-MET Effects

The psychedelic effects of 4-AcO–MET are thought to be due to its partial agonist activity at the 5-HT2A receptor. The role of these interactions in the psychedelic experience is still unknown.

This compound could also be quickly hydrolyzed to the 4-HO-MET free phenolic, but human studies on the metabolism of this drug are lacking. It would explain their subjective effects in a similar way. This would be similar to the way 4-AcO–DMT is thought deacetylated into 4-HO-DMT in first pass metabolism and subsequent liver passes.

Where to Buy 4-AcO-MET

Our website, Achemic, allows you to purchase research chemicals that include 4-AcO-MET. Before they are made available for sale, all our research chemicals have been tested and analyzed. This is the only way to ensure that our top-quality 4-AcO-MET products are available. We are happy to help you with any questions or provide further information.
This is for educational purposes only. Achemic will not sell 4-AcO-MET except for scientific and educational purposes. NOT for human consumption or veterinarian use. We ship to US and worldwide.


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